R62G (p.Arg62Gly) variant of REL (Proto-oncogene c-Rel)
R62G (p.Arg62Gly) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
R62G (p.Arg62Gly) variant details
- p.Arg62Gly
- gnomAD 2-60894427-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.54
- MetaLR 0.35
- MetaSVM -0.29
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available