P74H (p.Pro74His) variant of REL (Proto-oncogene c-Rel)
P74H (p.Pro74His) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
P74H (p.Pro74His) variant details
- p.Pro74His
- gnomAD 2-60894464-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.701
- REVEL 0.74
- MetaLR 0.41
- MetaSVM 0.00
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available