P16S (p.Pro16Ser) variant of REL (Proto-oncogene c-Rel)
P16S (p.Pro16Ser) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
P16S (p.Pro16Ser) variant details
- p.Pro16Ser
- rs751670419
- gnomAD 2-60891718-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.848
- REVEL 0.90
- MetaLR 0.76
- MetaSVM 0.78
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available