K73R (p.Lys73Arg) variant of REL (Proto-oncogene c-Rel)
K73R (p.Lys73Arg) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
K73R (p.Lys73Arg) variant details
- p.Lys73Arg
- gnomAD 2-60894461-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.16
- MetaLR 0.09
- MetaSVM -1.00
- CADD 23.40
- PolyPhen-2 0.91
- SIFT 0.76
- Population evidence available
- Structural context available
- Literature evidence available