K60R (p.Lys60Arg) variant of REL (Proto-oncogene c-Rel)
K60R (p.Lys60Arg) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
K60R (p.Lys60Arg) variant details
- p.Lys60Arg
- gnomAD 2-60894422-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.17
- MetaLR 0.10
- MetaSVM -1.01
- CADD 23.60
- PolyPhen-2 0.97
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available