K58N (p.Lys58Asn) variant of REL (Proto-oncogene c-Rel)
K58N (p.Lys58Asn) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
K58N (p.Lys58Asn) variant details
- p.Lys58Asn
- gnomAD 2-60894417-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.25
- MetaLR 0.17
- MetaSVM -0.95
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available