K26R (p.Lys26Arg) variant of REL (Proto-oncogene c-Rel)
K26R (p.Lys26Arg) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K26R (p.Lys26Arg) variant details
- p.Lys26Arg
- rs750889525
- gnomAD 2-60891749-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.36
- MetaLR 0.33
- MetaSVM -0.33
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available