K26N (p.Lys26Asn) variant of REL (Proto-oncogene c-Rel)
K26N (p.Lys26Asn) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
K26N (p.Lys26Asn) variant details
- p.Lys26Asn
- gnomAD 2-60891750-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.36
- MetaLR 0.31
- MetaSVM -0.54
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available