I35V (p.Ile35Val) variant of REL (Proto-oncogene c-Rel)
I35V (p.Ile35Val) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
I35V (p.Ile35Val) variant details
- p.Ile35Val
- rs1673221893
- gnomAD 2-60891775-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.43
- MetaLR 0.36
- MetaSVM -0.16
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available