H77Y (p.His77Tyr) variant of REL (Proto-oncogene c-Rel)
H77Y (p.His77Tyr) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
H77Y (p.His77Tyr) variant details
- p.His77Tyr
- gnomAD 2-60894472-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.78
- MetaLR 0.49
- MetaSVM 0.16
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available