G59V (p.Gly59Val) variant of REL (Proto-oncogene c-Rel)
G59V (p.Gly59Val) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
G59V (p.Gly59Val) variant details
- p.Gly59Val
- rs767728453
- gnomAD 2-60894419-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.25
- MetaLR 0.09
- MetaSVM -1.06
- CADD 23.20
- PolyPhen-2 0.83
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available