G59R (p.Gly59Arg) variant of REL (Proto-oncogene c-Rel)
G59R (p.Gly59Arg) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
G59R (p.Gly59Arg) variant details
- p.Gly59Arg
- gnomAD 2-60894418-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.22
- MetaLR 0.17
- MetaSVM -0.89
- CADD 23.90
- PolyPhen-2 0.89
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available