G59A (p.Gly59Ala) variant of REL (Proto-oncogene c-Rel)
G59A (p.Gly59Ala) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
G59A (p.Gly59Ala) variant details
- p.Gly59Ala
- rs767728453
- gnomAD 2-60894419-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.21
- MetaLR 0.06
- MetaSVM -1.06
- CADD 22.50
- PolyPhen-2 0.85
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available