G4S (p.Gly4Ser) variant of REL (Proto-oncogene c-Rel)
G4S (p.Gly4Ser) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
G4S (p.Gly4Ser) variant details
- p.Gly4Ser
- gnomAD 2-60881850-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.06
- MetaLR 0.11
- MetaSVM -1.01
- CADD 27.20
- PolyPhen-2 0.02
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available