G4C (p.Gly4Cys) variant of REL (Proto-oncogene c-Rel)
G4C (p.Gly4Cys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
G4C (p.Gly4Cys) variant details
- p.Gly4Cys
- gnomAD 2-60881850-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.08
- MetaLR 0.10
- MetaSVM -0.99
- CADD 33.00
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available