D70Y (p.Asp70Tyr) variant of REL (Proto-oncogene c-Rel)
D70Y (p.Asp70Tyr) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D70Y (p.Asp70Tyr) variant details
- p.Asp70Tyr
- gnomAD 2-60894451-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.29
- MetaLR 0.21
- MetaSVM -0.71
- CADD 26.20
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available