A91V (p.Ala91Val) variant of REL (Proto-oncogene c-Rel)
A91V (p.Ala91Val) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
A91V (p.Ala91Val) variant details
- p.Ala91Val
- gnomAD 2-60894515-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.23
- MetaLR 0.11
- MetaSVM -1.05
- CADD 24.10
- PolyPhen-2 0.96
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available