A91T (p.Ala91Thr) variant of REL (Proto-oncogene c-Rel)
A91T (p.Ala91Thr) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
A91T (p.Ala91Thr) variant details
- p.Ala91Thr
- gnomAD 2-60894514-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.21
- MetaLR 0.27
- MetaSVM -0.60
- CADD 27.70
- PolyPhen-2 0.99
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available