S25P (p.Ser25Pro) variant of RAI1 (Retinoic acid-induced protein 1)
S25P (p.Ser25Pro) in RAI1 (Retinoic acid-induced protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S25P (p.Ser25Pro) variant details
- p.Ser25Pro
- gnomAD 17-17793021-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.13
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 20.90
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available