P66L (p.Pro66Leu) variant of RAI1 (Retinoic acid-induced protein 1)
P66L (p.Pro66Leu) in RAI1 (Retinoic acid-induced protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P66L (p.Pro66Leu) variant details
- p.Pro66Leu
- gnomAD rs1418405708
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 19.60
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available