P66A (p.Pro66Ala) variant of RAI1 (Retinoic acid-induced protein 1)
P66A (p.Pro66Ala) in RAI1 (Retinoic acid-induced protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P66A (p.Pro66Ala) variant details
- p.Pro66Ala
- gnomAD rs1249978176
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.06
- CADD 8.14
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available