L46I (p.Leu46Ile) variant of RAI1 (Retinoic acid-induced protein 1)
L46I (p.Leu46Ile) in RAI1 (Retinoic acid-induced protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L46I (p.Leu46Ile) variant details
- p.Leu46Ile
- gnomAD rs1264382724
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 22.80
- PolyPhen-2 0.34
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available