F4S (p.Phe4Ser) variant of RAI1 (Retinoic acid-induced protein 1)
F4S (p.Phe4Ser) in RAI1 (Retinoic acid-induced protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
F4S (p.Phe4Ser) variant details
- p.Phe4Ser
- gnomAD rs1168751598
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- REVEL 0.66
- ESM-1b 0.00
- AlphaMissense 1.00
- CADD 28.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available