L84F (p.Leu84Phe) variant of RAG2 (P55895)
L84F (p.Leu84Phe) in RAG2 (P55895) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L84F (p.Leu84Phe) variant details
- p.Leu84Phe
- ExAC rs761118163
- gnomAD rs761118163
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.28
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available