I61V (p.Ile61Val) variant of RAG2 (P55895)
I61V (p.Ile61Val) in RAG2 (P55895) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, and structural context.
I61V (p.Ile61Val) variant details
- p.Ile61Val
- ExAC rs780915477
- gnomAD rs780915477
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.27
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- RAG2 Recombination activating protein 2, PHD domain domainome 1.0: score -0.159