E85G (p.Glu85Gly) variant of RAG2 (P55895)
E85G (p.Glu85Gly) in RAG2 (P55895) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
E85G (p.Glu85Gly) variant details
- p.Glu85Gly
- gnomAD 11-36593915-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.25
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available