Y38F (p.Tyr38Phe) variant of RAF1 (P04049)
Y38F (p.Tyr38Phe) in RAF1 (P04049) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y38F (p.Tyr38Phe) variant details
- p.Tyr38Phe
- gnomAD 14-20891865-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.09
- MetaLR 0.06
- MetaSVM -1.05
- CADD 5.75
- PolyPhen-2 0.04
- SIFT 0.08
- Population evidence available
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.267
- Literature evidence available