Y38D (p.Tyr38Asp) variant of RAF1 (P04049)
Y38D (p.Tyr38Asp) in RAF1 (P04049) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y38D (p.Tyr38Asp) variant details
- p.Tyr38Asp
- rs1400166609
- gnomAD 14-20891864-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.15
- MetaLR 0.16
- MetaSVM -1.00
- CADD 21.50
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.267
- Literature evidence available