T49N (p.Thr49Asn) variant of RAF1 (P04049)
T49N (p.Thr49Asn) in RAF1 (P04049) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T49N (p.Thr49Asn) variant details
- p.Thr49Asn
- rs774318039
- gnomAD 14-20891838-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0753
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -0.96
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.332
- Literature evidence available