S25S (p.Ser25Ser) variant of RAF1 (P04049)
S25S (p.Ser25Ser) in RAF1 (P04049) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S25S (p.Ser25Ser) variant details
- p.Ser25Ser
- rs1335962557
- gnomAD 14-20891758-A-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0825
- CADD 0.26
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -1.01
- Literature evidence available