R59R (p.Arg59Arg) variant of RAF1 (P04049)
R59R (p.Arg59Arg) in RAF1 (P04049) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R59R (p.Arg59Arg) variant details
- p.Arg59Arg
- rs115812876
- gnomAD 14-20891849-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0822
- CADD 0.22
- Most common in the African/African-American population (allele frequency 2.5e-05)
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.717
- Literature evidence available