R59* (p.Arg59Ter) variant of RAF1 (P04049)
R59* (p.Arg59Ter) in RAF1 (P04049) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R59* (p.Arg59Ter) variant details
- p.Arg59Ter
- rs183860442
- gnomAD 14-20891867-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.249
- CADD 23.70
- Most common in the 1KG:FIN population (allele frequency 0.0051)
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.717
- Literature evidence available