R41* (p.Arg41Ter) variant of RAF1 (P04049)
R41* (p.Arg41Ter) in RAF1 (P04049) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R41* (p.Arg41Ter) variant details
- p.Arg41Ter
- rs1877565766
- gnomAD 14-20891831-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.268
- CADD 26.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -1.03
- Literature evidence available