P51T (p.Pro51Thr) variant of RAF1 (P04049)
P51T (p.Pro51Thr) in RAF1 (P04049) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P51T (p.Pro51Thr) variant details
- p.Pro51Thr
- rs1230787360
- gnomAD 14-20891825-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.91
- CADD 0.00
- PolyPhen-2 0.17
- SIFT 0.47
- Population evidence available
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.298
- Literature evidence available