P30T (p.Pro30Thr) variant of RAF1 (P04049)
P30T (p.Pro30Thr) in RAF1 (P04049) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P30T (p.Pro30Thr) variant details
- p.Pro30Thr
- gnomAD 14-20891771-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -1.10
- CADD 13.10
- PolyPhen-2 1.00
- SIFT 0.06
- Population evidence available
- Structural context available
- RAF1 Raf-like Ras-binding domain domainome 1.0: score -0.168
- Literature evidence available