M3V (p.Met3Val) variant of RAD51 (Q06609)
M3V (p.Met3Val) in RAD51 (Q06609) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M3V (p.Met3Val) variant details
- p.Met3Val
- rs751792276
- ClinGen CA7483899
- ClinVar RCV003725520
- ExAC rs751792276
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.18
- CADD 17.50
- PolyPhen-2 0.00
- SIFT 0.14
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Population evidence available
- Structural context available