Y67C (p.Tyr67Cys) variant of RAD21 (O60216)
Y67C (p.Tyr67Cys) in RAD21 (O60216) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
Y67C (p.Tyr67Cys) variant details
- p.Tyr67Cys
- Ensembl rs1812625618
- Missense
- Variant Prioritization Score for Impact Estimate 0.758
- REVEL 0.82
- CADD 29.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available