T199I (p.Thr199Ile) variant of RAD21 (O60216)
T199I (p.Thr199Ile) in RAD21 (O60216) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
T199I (p.Thr199Ile) variant details
- p.Thr199Ile
- TOPMed rs1261006144
- gnomAD rs1261006144
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.06
- CADD 22.60
- PolyPhen-2 0.08
- SIFT 0.12
- Most common in the South Asian population (allele frequency 1.2e-05)