S198N (p.Ser198Asn) variant of RAD21 (O60216)
S198N (p.Ser198Asn) in RAD21 (O60216) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
S198N (p.Ser198Asn) variant details
- p.Ser198Asn
- TOPMed rs905200346
- gnomAD rs905200346
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.06
- CADD 21.30
- PolyPhen-2 0.11
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 6e-05)