E157D (p.Glu157Asp) variant of RAD21 (O60216)
E157D (p.Glu157Asp) in RAD21 (O60216) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data.
E157D (p.Glu157Asp) variant details
- p.Glu157Asp
- TOPMed rs1812515621
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.07
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)