D181N (p.Asp181Asn) variant of RAD21 (O60216)
D181N (p.Asp181Asn) in RAD21 (O60216) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
D181N (p.Asp181Asn) variant details
- p.Asp181Asn
- TOPMed rs1462000579
- gnomAD rs1462000579
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.06
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the Middle Eastern population (allele frequency 0.00018)