V8L (p.Val8Leu) variant of RAC1 (P63000)
V8L (p.Val8Leu) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
V8L (p.Val8Leu) variant details
- p.Val8Leu
- gnomAD 7-6374757-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.28
- CADD 23.70
- PolyPhen-2 0.13
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available