V8E (p.Val8Glu) variant of RAC1 (P63000)
V8E (p.Val8Glu) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
V8E (p.Val8Glu) variant details
- p.Val8Glu
- gnomAD 7-6374758-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- REVEL 0.75
- CADD 32.00
- PolyPhen-2 0.93
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available