T17A (p.Thr17Ala) variant of RAC1 (P63000)
T17A (p.Thr17Ala) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
T17A (p.Thr17Ala) variant details
- p.Thr17Ala
- gnomAD 7-6387225-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.82
- CADD 25.70
- PolyPhen-2 0.56
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available