L20Q (p.Leu20Gln) variant of RAC1 (P63000)
L20Q (p.Leu20Gln) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
L20Q (p.Leu20Gln) variant details
- p.Leu20Gln
- 1000Genomes rs565555925
- ExAC rs565555925
- gnomAD rs565555925
- Missense
- Variant Prioritization Score for Impact Estimate 0.784
- REVEL 0.89
- CADD 27.50
- PolyPhen-2 0.79
- SIFT 0.01
- Population evidence available
- Structural context available