L20M (p.Leu20Met) variant of RAC1 (P63000)
L20M (p.Leu20Met) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
L20M (p.Leu20Met) variant details
- p.Leu20Met
- gnomAD 7-6387234-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.618
- REVEL 0.63
- CADD 24.70
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available