L19V (p.Leu19Val) variant of RAC1 (P63000)
L19V (p.Leu19Val) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
L19V (p.Leu19Val) variant details
- p.Leu19Val
- gnomAD rs1381712962
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.69
- CADD 25.10
- PolyPhen-2 0.23
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available