I4V (p.Ile4Val) variant of RAC1 (P63000)
I4V (p.Ile4Val) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
I4V (p.Ile4Val) variant details
- p.Ile4Val
- gnomAD 7-6374745-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.15
- CADD 22.00
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available