I4T (p.Ile4Thr) variant of RAC1 (P63000)
I4T (p.Ile4Thr) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
I4T (p.Ile4Thr) variant details
- p.Ile4Thr
- gnomAD 7-6374746-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.46
- CADD 26.40
- PolyPhen-2 0.61
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available