I33M (p.Ile33Met) variant of RAC1 (P63000)
I33M (p.Ile33Met) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
I33M (p.Ile33Met) variant details
- p.Ile33Met
- TOPMed rs1240617392
- gnomAD rs1240617392
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.60
- CADD 22.80
- PolyPhen-2 0.89
- SIFT 0.01
- Population evidence available
- Structural context available